Expert Solutions for Drug Discovery Problems
We Provide Targeted Strategies to Overcome Your Toughest R&D Challenges
Accelerating Drug Discovery, Delivering Breakthroughs
Who We Are
At ShankarV Rx LLC, we bring over 20 years of proven leadership in drug discovery. From 7 IND filings to an FDA-approved therapy (Revumenib), we’ve successfully advanced programs across oncology, neurology, immunology, and metabolic diseases. Our consulting services are designed to help you overcome bottlenecks, optimize strategies, and maximize R&D investments.
What We Do
Target Selection & Validation
Confidently choose the right targets with in-depth scientific and clinical assessments.
Hit Identification & Optimization
Expertise in SBDD, FBDD, HTS, DEL, and cheminformatics to find high-quality leads quickly.
Lead Optimization
Driving molecules to candidates through SAR, potency, selectivity, and ADMET balance.
Preclinical Strategy
Translational study design that bridges discovery with IND-enabling development.
Innovative Modalities
PROTACs, molecular glues, cyclic peptides, and covalent/allosteric modulators.
Data & Portfolio Review
Integrating chemistry, biology, DMPK, and safety to prioritize next steps.
Supporting academia
Supporting academia, and non-profit organizations, to assist in the identification of high-quality development candidates to enable reliable testing of therapeutic hypotheses in the clinic
Supporting Early Start Up
Supporting early start up companies with funding, research plans, sourcing of CROs for research etc.
Why Work With Us—Proven Impact
